¹²⁹ Xe and Free-Breathing ¹ H Ventilation MRI in Patients With Cystic Fibrosis: A Dual-Center Study.

ABSTRACT:

Background

Free-breathing ¹ H ventilation MRI shows promise but only single-center validation has yet been performed against methods which directly image lung ventilation in patients with cystic fibrosis (CF).

Purpose

To investigate the relationship between ¹²⁹ Xe and ¹ H ventilation images using data acquired at two centers.

Study type

Sequence comparison.

Population

Center 1; 24 patients with CF (12 female) aged 9-47 years. Center 2; 7 patients with CF (6 female) aged 13-18 years, and 6 healthy controls (6 female) aged 21-31 years. Data were acquired in different patients at each center.

Field strength/sequence

1.5 T, 3D steady-state free precession and 2D spoiled gradient echo.

Assessment

Subjects were scanned w

SUBMITTER: Marshall H 

PROVIDER: S-EPMC10946578 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature