Phenotype, outcomes and natural history of early-stage non-ischaemic cardiomyopathy.

ABSTRACT:

Aims

To characterize the phenotype, clinical outcomes and rate of disease progression in patients with early-stage non-ischaemic cardiomyopathy (early-NICM).

Methods and results

We conducted a prospective observational cohort study of patients with early-NICM assessed by late gadolinium enhancement cardiovascular magnetic resonance (CMR). Cases were classified into the following subgroups: isolated left ventricular dilatation (early-NICM H-/D+), non-dilated left ventricular cardiomyopathy (early-NICM H+/D-), or early dilated cardiomyopathy (early-NICM H+/D+). Clinical follow-up for major adverse cardiovascular events (MACE) included non-fatal life-threatening arrhythmia, unplanned cardiovascular hospitalization or cardiovascular death. A subset of patients (n = 119) underwen

SUBMITTER: Hammersley DJ 

PROVIDER: S-EPMC10946699 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature