Joint radial trajectory correction for accelerated T₂ ^* mapping on an MR-Linac.

ABSTRACT:

Background

T₂ ^* mapping can characterize tumor hypoxia, which may be associated with resistance to therapy. Acquiring T₂ ^* maps during MR-guided radiotherapy could inform treatment adaptation by, for example, escalating the dose to resistant sub-volumes.

Purpose

The purpose of this work is to demonstrate the feasibility of the accelerated T₂ ^* mapping technique using model-based image reconstruction with integrated trajectory auto-correction (TrACR) for MR-guided radiotherapy on an MR-Linear accelerator (MR-Linac).

Materials and methods

The proposed method was validated in a numerical phantom, where two T₂ ^* mapping approaches (sequential and joint) were compared for different nois

SUBMITTER: Bano W 

PROVIDER: S-EPMC10946747 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature