Ontology highlight
ABSTRACT:
SUBMITTER: Saeed HK
PROVIDER: S-EPMC10946911 | biostudies-literature | 2023 Jun
REPOSITORIES: biostudies-literature
Saeed Hiwa K HK Jarman Paul J PJ Sreedharan Sreejesh S Mowll Rachel R Auty Alexander J AJ Chauvet Adrien A P AAP Smythe Carl G W CGW de la Serna Jorge Bernardino JB Thomas Jim A JA
Chemistry (Weinheim an der Bergstrasse, Germany) 20230502 34
The synthesis of a new heterodinuclear Re<sup>I</sup> Ru<sup>II</sup> metallointercalator containing Ru<sup>II</sup> (dppz) and Re<sup>I</sup> (dppn) moieties is reported. Cell-free studies reveal that the complex has similar photophysical properties to its homoleptic M(dppz) analogue and it also binds to DNA with a similar affinity. However, the newly reported complex has very different in-cell properties to its parent. In complete contrast to the homoleptic system, the Ru<sup>II</sup> (dppz)/R ...[more]