Small for gestational age is associated with reduced lung function in middle age: A prospective study from first to fifth decade of life.

ABSTRACT:

Background and objective

The association between birth weight, particularly relative to gestational age, and adult lung function is uncertain. We investigated the associations between birth weight relative to gestational age and measures of lung function in middle age, and mediation of these associations by adult height.

Methods

Participants in the Tasmanian Longitudinal Health Study who had both known birth weight and lung function assessment at age 45 years were included (n = 849). Linear regression models were fitted to investigate the association between small for gestational age and birth weight with post-bronchodilator lung function measures (forced expiratory volume in 1 second [FEV₁ ], forced vital capacity [FVC], FEV₁ /FVC, diffusing capacity f

SUBMITTER: Tandra M 

PROVIDER: S-EPMC10947040 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature