Early emollient bathing is associated with subsequent atopic dermatitis in an unselected birth cohort study.

ABSTRACT:

Background

Skin barrier dysfunction is a key component of the pathogenesis of atopic dermatitis (AD). Recent research on barrier optimization to prevent AD has shown mixed results. The aim of this study was to assess the relationship between emollient bathing at 2 months and the trajectory of AD in the first 2 years of life in a large unselected observational birth cohort study.

Methods

The Babies After SCOPE: Evaluating the Longitudinal Impact Using Neurological and Nutritional Endpoints Birth Cohort study enrolled 2183 infants. Variables extracted from the database related to early skincare, skin barrier function, parental history of atopy, and AD outcomes. Statistical analysis was performed to adjust for potential confounding variables.

Results

One thousand five hu

SUBMITTER: O'Connor C 

PROVIDER: S-EPMC10947084 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature