The impact of antenatal and postnatal indoor air pollution or tobacco smoke exposure on lung function at 3 years in an African birth cohort.

ABSTRACT:

Background and objective

Indoor air pollution (IAP) and tobacco smoke exposure (ETS) are global health concerns contributing to the burden of childhood respiratory disease. Studies assessing the effects of IAP and ETS in preschool children are limited. We assessed the impact of antenatal and postnatal IAP and ETS exposure on lung function in a South African birth cohort, the Drakenstein Child Health Study.

Methods

Antenatally enrolled mother-child pairs were followed from birth. Lung function measurements (oscillometry, multiple breath washout and tidal breathing) were performed at 6 weeks and 3 years. Quantitative antenatal and postnatal IAP (particulate matter [PM₁₀ ], volatile organic compounds [VOC]) and ETS exposures were measured. Linear regression models ex

SUBMITTER: Chaya S 

PROVIDER: S-EPMC10947154 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature