Exploring optimal settings for safe and effective thulium fibre laser lithotripsy in a kidney model.

ABSTRACT:

Objectives

To explore the optimal laser settings and treatment strategies for thulium fibre laser (TFL) lithotripsy, namely, those with the highest treatment efficiency, lowest thermal injury risk, and shortest procedure time.

Materials and methods

An in vitro kidney model was used to assess the efficacy of TFL lithotripsy in the upper calyx. Stone ablation experiments were performed on BegoStone phantoms at different combinations of pulse energy (E_P ) and frequency (F) to determine the optimal settings. Temperature changes and thermal injury risks were monitored using embedded thermocouples. Experiments were also performed on calcium oxalate monohydrate (COM) stones to validate the optimal settings.

Results

High E_P /low F settings demonstrated s

SUBMITTER: Mishra A 

PROVIDER: S-EPMC10947524 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature