Connections between reproductive health and cognitive aging among women enrolled in the HCHS/SOL and SOL-INCA.

ABSTRACT:

Introduction

Reproductive health history may contribute to cognitive aging and risk for Alzheimer's disease, but this is understudied among Hispanic/Latina women.

Methods

Participants included 2126 Hispanic/Latina postmenopausal women (44 to 75 years) from the Study of Latinos-Investigation of Neurocognitive Aging. Survey linear regressions separately modeled the associations between reproductive health measures (age at menarche, history of oral contraceptive use, number of pregnancies, number of live births, age at menopause, female hormone use at Visit 1, and reproductive span) with cognitive outcomes at Visit 2 (performance, 7-year change, and mild cognitive impairment [MCI] prevalence).

Results

Younger age at menarche, oral contraceptive use, lower pregnancies, lo

SUBMITTER: Stickel AM 

PROVIDER: S-EPMC10947951 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature