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Gel immersion endoscopic mucosal resection for early gastric neoplasms: a multicenter case series study.


ABSTRACT: Several cases have been reported that suggest the efficacy of gel immersion endoscopic mucosal resection (GI-EMR) for gastric neoplasms. However, no study has evaluated treatment outcomes of GI-EMR for gastric neoplasms. This study aimed to investigate the efficacy and safety of GI-EMR for early gastric neoplasms. Nine patients (17 lesions) undergoing gastric GI-EMR were included, with a median lesion size of 10 mm (interquartile range [IQR] 5-13 mm). All lesions were protruding or flat elevated. The median procedure time was 3 minutes (IQR 2-5) and en bloc resection was achieved in all cases. Among 15 neoplastic lesions, the R0 resection rate was 86.7% (13/15 lesions). Adverse events included immediate bleeding requiring hemostasis in two cases, which was controlled endoscopically. No delayed bleeding or perforation occurred. In conclusion, GI-EMR may be a safe and effective treatment for early, small gastric neoplasms. However, due to the small sample in the present study, further investigation is required regarding the indication for this technique.

SUBMITTER: Kimura H 

PROVIDER: S-EPMC10948274 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature

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Gel immersion endoscopic mucosal resection for early gastric neoplasms: a multicenter case series study.

Kimura Hidenori H   Yamamoto Yoichi Y   Yabuuchi Yohei Y   Shigeta Kohei K   Yoshida Masao M   Nagao Soichiro S   Noguchi Akito A   Morita Yukihiro Y   Shintani Shuhei S   Inatomi Osamu O   Ono Hiroyuki H   Andoh Akira A  

Endoscopy international open 20240318 3


Several cases have been reported that suggest the efficacy of gel immersion endoscopic mucosal resection (GI-EMR) for gastric neoplasms. However, no study has evaluated treatment outcomes of GI-EMR for gastric neoplasms. This study aimed to investigate the efficacy and safety of GI-EMR for early gastric neoplasms. Nine patients (17 lesions) undergoing gastric GI-EMR were included, with a median lesion size of 10 mm (interquartile range [IQR] 5-13 mm). All lesions were protruding or flat elevated  ...[more]

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