Effect of Bacillus subtilis and Bacillus coagulans spores on induced allergic contact dermatitis in dogs.

ABSTRACT:

Background

Probiotic strains have the potential to modulate immune responses, reduce intestinal inflammation, normalize intestinal mucosal function and decrease allergic reactions.

Objective

This study aimed to investigate the effect of oral probiotic supplements containing Bacillus subtilis and Bacillus coagulans spores on clinical symptoms, haematological factors and immune responses to allergic contact dermatitis in dogs induced by dinitrochlorobenzene (DNCB).

Methods

DNCB was injected subcutaneously into the scapular region of 20 healthy adult dogs of both sexes, divided into four groups, to induce experimental allergic contact dermatitis. Dogs in Group 1 received food without probiotics or medication. Oral prednisolone was administered to Group 2 for 30 days at a

SUBMITTER: Khosravi M 

PROVIDER: S-EPMC10949178 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature