Ontology highlight
ABSTRACT: Importance
Fruiting bodies of mushroom-forming fungi (Agaricomycetes) are complex multicellular structures, with a spatially and temporally integrated developmental program that is, however, currently poorly known. In this study, we present a novel, conserved gene family, Snowball (snb), termed after the unique, differentiation-less fruiting body morphology of snb1 knockout strains in the model mushroom Coprinopsis cinerea. snb is a gene of unknown function that is highly conserved among agaricomycetes and encodes a protein of unknown function. A comparative transcriptomic analysis of the early developmental stages of differentiated wild-type and non-differentiated mutant fruiting bodies revealed conserved differentially expressed genes which may be related to tissue differentiation and developmental patterning fruiting body development.
SUBMITTER: Foldi C
PROVIDER: S-EPMC10949477 | biostudies-literature | 2024 Mar
REPOSITORIES: biostudies-literature
mSystems 20240209 3
The morphogenesis of sexual fruiting bodies of fungi is a complex process determined by a genetically encoded program. Fruiting bodies reached the highest complexity levels in the Agaricomycetes; yet, the underlying genetics is currently poorly known. In this work, we functionally characterized a highly conserved gene termed <i>snb1</i>, whose expression level increases rapidly during fruiting body initiation. According to phylogenetic analyses, orthologs of <i>snb1</i> are present in almost all ...[more]