ElemeNT 2023: an enhanced tool for detection and curation of core promoter elements.

ABSTRACT:

Motivation

Prediction and identification of core promoter elements and transcription factor binding sites is essential for understanding the mechanism of transcription initiation and deciphering the biological activity of a specific locus. Thus, there is a need for an up-to-date tool to detect and curate core promoter elements/motifs in any provided nucleotide sequences.

Results

Here, we introduce ElemeNT 2023-a new and enhanced version of the Elements Navigation Tool, which provides novel capabilities for assessing evolutionary conservation and for readily evaluating the quality of high-throughput transcription start site (TSS) datasets, leveraging preferential motif positioning. ElemeNT 2023 is accessible both as a fast web-based tool and via command line (no coding skills

SUBMITTER: Adato O 

PROVIDER: S-EPMC10950481 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature