Pallidal versus subthalamic deep brain stimulation for Meige syndrome: A systematic review and meta-analysis.

ABSTRACT:

Background

Globus pallidus internus (GPi) and subthalamic nucleus (STN) are two common deep brain stimulation (DBS) targets. This meta-analysis was to compared the efficacy and safety of these two DBS targets for the treatment of Meige syndrome (MS).

Methods

A systematic search was performed using EMBASE, MEDLINE, the Cochrane Library, and ClinicalTrials.gov to identify DBS trials for MS. Review Manager 5.3 was used to perform meta-analysis and the mean difference (MD) was analyzed and calculated with a random effect model. Pearson's correlation coefficients and meta-regression analyses were utilized to identify relevant predictive markers.

Results

Twenty trials involving 188 participants with GPi-DBS and 110 individuals with STN-DBS were eligible. Both groups showed

SUBMITTER: Wu X 

PROVIDER: S-EPMC10950702 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature