Delipid extracorporeal lipoprotein filter from plasma system: a new intensive lipid lowering therapy for patients with acute ischemic stroke.

ABSTRACT:

Objectives

To investigate the safety and efficacy of the delipid extracorporeal lipoprotein filter from plasma (DELP) system, a new low-density lipoprotein cholesterol (LDL-C) adsorption system, in acute ischemic stroke (AIS) patients.

Patients and methods

In the present study, a total of 180 AIS patients were enrolled during March 2019 to February 2021. They were divided into DELP group (n₁ = 90) and the control group (n₂ = 90). The treatment protocol and vascular access of DELP treatment was established and evaluated. For the DELP group, clinical data and laboratory results including plasma lipid and safety parameters before and after the apheresis were collected and analyzed. For all participants, neurological scores were assessed and r

SUBMITTER: Jiao Y 

PROVIDER: S-EPMC10950928 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature