Cerebellum Lecture: the Cerebellar Nuclei-Core of the Cerebellum.

ABSTRACT: The cerebellum is a key player in many brain functions and a major topic of neuroscience research. However, the cerebellar nuclei (CN), the main output structures of the cerebellum, are often overlooked. This neglect is because research on the cerebellum typically focuses on the cortex and tends to treat the CN as relatively simple output nuclei conveying an inverted signal from the cerebellar cortex to the rest of the brain. In this review, by adopting a nucleocentric perspective we aim to rectify this impression. First, we describe CN anatomy and modularity and comprehensively integrate CN architecture with its highly organized but complex afferent and efferent connectivity. This is followed by a novel classification of the specific neuronal classes the CN comprise and speculate on the i

SUBMITTER: Kebschull JM 

PROVIDER: S-EPMC10951048 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature