Serum S100B Level in the Management of Pediatric Minor Head Trauma: A Randomized Clinical Trial.

ABSTRACT:

Importance

Minor head trauma (HT) is one of the most common causes of hospitalization in children. A diagnostic test could prevent unnecessary hospitalizations and cranial computed tomographic (CCT) scans.

Objective

To evaluate the effectiveness of serum S100B values in reducing exposure to CCT scans and in-hospital observation in children with minor HT.

Design, setting, and participants

This multicenter, unblinded, prospective, interventional randomized clinical trial used a stepped-wedge cluster design to compare S100B biomonitoring and control groups at 11 centers in France. Participants included children and adolescents 16 years or younger (hereinafter referred to as children) admitted to the emergency department with minor HT. The enrollment period was November 1

SUBMITTER: Bouvier D 

PROVIDER: S-EPMC10951739 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature