Primary outcome reporting in clinical trials for older adults with depression.

ABSTRACT:

Background

Findings from randomised controlled trials (RCTs) are synthesised through meta-analyses, which inform evidence-based decision-making. When key details regarding trial outcomes are not fully reported, knowledge synthesis and uptake of findings into clinical practice are impeded.

Aims

Our study assessed reporting of primary outcomes in RCTs for older adults with major depressive disorder (MDD).

Method

Trials published between 2011 and 2021, which assessed any intervention for adults aged ≥65 years with a MDD diagnosis, and that specified a single primary outcome were considered for inclusion in our study. Outcome reporting assessment was conducted independently and in duplicate with a 58-item checklist, used in developing the CONSORT-Outcomes statement, and i

SUBMITTER: Rodrigues M 

PROVIDER: S-EPMC10951853 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature