Incidence and associations of hospital delirium diagnoses in 85,979 people with severe mental illness: A data linkage study.

ABSTRACT:

Introduction

Delirium is an acute neuro-psychiatric disturbance precipitated by a range of physical stressors, with high morbidity and mortality. Little is known about its relationship with severe mental illness (SMI).

Methods

We conducted a retrospective cohort study using linked data analyses of the UK Clinical Practice Research Datalink (CPRD) and Hospital Episodes Statistics (HES) databases. We ascertained yearly hospital delirium incidence from 2000 to 2017 and used logistic regression to identify associations with delirium diagnosis in a population with SMI.

Results

The cohort included 249,047 people with SMI with median follow-up time in CPRD of 6.4 years. A total of 85,979 patients were eligible for linkage to HES. Delirium incidence increased from 0.04 (95% C

SUBMITTER: Bauernfreund Y 

PROVIDER: S-EPMC10952251 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature