Ontology highlight
ABSTRACT:
SUBMITTER: Vollheyde K
PROVIDER: S-EPMC10952274 | biostudies-literature | 2023 Oct
REPOSITORIES: biostudies-literature
Vollheyde Katharina K Dudley Quentin M QM Yang Ting T Oz Mehmet T MT Mancinotti Davide D Fedi Mariano Olivera MO Heavens Darren D Linsmith Gareth G Chhetry Monika M Smedley Mark A MA Harwood Wendy A WA Swarbreck David D Geu-Flores Fernando F Patron Nicola J NJ
The New phytologist 20230724 1
The model plant Nicotiana benthamiana is an increasingly attractive organism for the production of high-value, biologically active molecules. However, N. benthamiana accumulates high levels of pyridine alkaloids, in particular nicotine, which complicates the downstream purification processes. Here, we report a new assembly of the N. benthamiana genome as well as the generation of low-nicotine lines by CRISPR/Cas9-based inactivation of berberine bridge enzyme-like proteins (BBLs). Triple as well ...[more]