Anthropogenic contamination sources drive differences in antimicrobial-resistant Escherichia coli in three urban lakes.

ABSTRACT: Antimicrobial resistance (AMR) is an ever-present threat to the treatment of infectious diseases. However, the potential relevance of this phenomenon in environmental reservoirs still raises many questions. Detection of antimicrobial-resistant bacteria in the environment is a critical aspect for understanding the prevalence of resistance outside of clinical settings, as detection in the environment indicates that resistance is likely already widespread. We isolated antimicrobial-resistant Escherichia coli from three urban waterbodies over a 15-month time series, determined their antimicrobial susceptibilities, investigated their population structure, and identified genetic determinants of resistance. We found that E. coli populations at each site were composed of different do

SUBMITTER: Wight J 

PROVIDER: S-EPMC10952509 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature