The catabolism of lignin-derived p-methoxylated aromatic compounds by Rhodococcus jostii RHA1.

ABSTRACT: Emergent strategies to valorize lignin, an abundant but underutilized aromatic biopolymer, include tandem processes that integrate chemical depolymerization and biological catalysis. To date, aromatic monomers from C-O bond cleavage of lignin have been converted to bioproducts, but the presence of recalcitrant C-C bonds in lignin limits the product yield. A promising chemocatalytic strategy that overcomes this limitation involves phenol methyl protection and autoxidation. Incorporating this into a tandem process requires microbial cell factories able to transform the p-methoxylated products in the resulting methylated lignin stream. In this study, we assessed the ability of Rhodococcus jostii RHA1 to catabolize the major aromatic products in a methylated lignin stream and elu

SUBMITTER: Wolf ME 

PROVIDER: S-EPMC10952524 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature