Childhood sleep health and epigenetic age acceleration in late adolescence: Cross-sectional and longitudinal analyses.

ABSTRACT:

Aim

Investigate if childhood measures of sleep health are associated with epigenetic age acceleration in late adolescence.

Methods

Parent-reported sleep trajectories from age 5 to 17, self-reported sleep problems at age 17, and six measures of epigenetic age acceleration at age 17 were studied in 1192 young Australians from the Raine Study Gen2.

Results

There was no evidence for a relationship between the parent-reported sleep trajectories and epigenetic age acceleration (p ≥ 0.17). There was a positive cross-sectional relationship between self-reported sleep problem score and intrinsic epigenetic age acceleration at age 17 (b = 0.14, p = 0.04), which was attenuated after controlling for depressive symptom score at the same age (b = 0.08, p = 0.34). Follow-up analyses

SUBMITTER: Balfour D 

PROVIDER: S-EPMC10952569 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature