Optimization of 4D combined angiography and perfusion using radial imaging and arterial spin labeling.

ABSTRACT:

Purpose

To extend and optimize a non-contrast MRI technique to obtain whole head 4D (time-resolved 3D) qualitative angiographic and perfusion images from a single scan.

Methods

4D combined angiography and perfusion using radial imaging and arterial spin labeling (CAPRIA) uses pseudocontinuous labeling with a 3D golden ratio ("koosh ball") readout to continuously image the blood water as it travels through the arterial system and exchanges into the tissue. High spatial/temporal resolution angiograms and low spatial/temporal resolution perfusion images can be flexibly reconstructed from the same raw k-space data. Constant and variable flip angle (CFA and VFA, respectively) excitation schedules were optimized through simulations and tested in healthy volunteers. A conventional

SUBMITTER: Okell TW 

PROVIDER: S-EPMC10952652 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature