Removing hepatitis C antibody testing for Australian blood donations: A cost-effectiveness analysis.

ABSTRACT:

Background and objectives

The risk of transfusion-transmitted hepatitis C virus (HCV) infections is extremely low in Australia. This study aims to conduct a cost-effectiveness analysis of different testing strategies for HCV infection in blood donations.

Materials and methods

The four testing strategies evaluated in this study were universal testing with both HCV antibody (anti-HCV) and nucleic acid testing (NAT); anti-HCV and NAT for first-time donations and NAT only for repeat donations; anti-HCV and NAT for transfusible component donations and NAT only for plasma for further manufacture; and universal testing with NAT only. A decision-analytical model was developed to assess the cost-effectiveness of alternative HCV testing strategies. Sensitivity analysis and threshold a

SUBMITTER: Cheng Q 

PROVIDER: S-EPMC10952740 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature