Dynamics of mRNA fate during light stress and recovery: from transcription to stability and translation.

ABSTRACT: Transcript stability is an important determinant of its abundance and, consequently, translational output. Transcript destabilisation can be rapid and is well suited for modulating the cellular response. However, it is unclear the extent to which RNA stability is altered under changing environmental conditions in plants. We previously hypothesised that recovery-induced transcript destabilisation facilitated a phenomenon of rapid recovery gene downregulation (RRGD) in Arabidopsis thaliana (Arabidopsis) following light stress, based on mathematical calculations to account for ongoing transcription. Here, we test this hypothesis and investigate processes regulating transcript abundance and fate by quantifying changes in transcription, stability and translation before, during and after light s

SUBMITTER: Smith AB 

PROVIDER: S-EPMC10952913 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature