Choosing and evaluating randomisation methods in clinical trials: a qualitative study.

ABSTRACT:

Background

There exist many different methods of allocating participants to treatment groups during a randomised controlled trial. Although there is research that explores trial characteristics that are associated with the choice of method, there is still a lot of variety in practice not explained. This study used qualitative methods to explore more deeply the motivations behind researchers' choice of randomisation, and which features of the method they use to evaluate the performance of these methods.

Methods

Data was collected from online focus groups with various stakeholders involved in the randomisation process. Focus groups were recorded and then transcribed verbatim. A thematic analysis was used to analyse the transcripts.

Results

Twenty-five participants from

SUBMITTER: Bruce CL 

PROVIDER: S-EPMC10953118 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature