Biochemical changes in lumbar facet joint and disc degeneration by T2* mapping.

ABSTRACT:

Background

To investigate the biochemical changes in lumbar facet joint (LFJ) and intervertebral disc (IVD) with different degenerative grade by T2* mapping.

Methods

Sixty-eight patients with low back pain (study group) and 20 volunteers (control group) underwent standard MRI protocols and axial T2* mapping. Morphological evaluation of LFJ and IVD were performed on T2-weighted imaging according to Weishaupt and Pfirrmann grading system, respectively. T2* values of LFJ and of AF (anterior annulus fibrosus), NP (nucleus pulposus), and PF (posterior annulus fibrosus) in IVD were measured. Kruskal-Wallis test and Wilcoxon rank-sum test were used to compare T2* values of subjects with different degenerative grade.

Results

The mean T2* value of grade 0 LFJ (21.68[17.77,26.1

SUBMITTER: Ding Y 

PROVIDER: S-EPMC10953206 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature