Atrial Fibrillation Detected before or after Stroke: Role of Anticoagulation.

ABSTRACT:

Background

Atrial fibrillation (AF) known before ischemic stroke (KAF) has been postulated to be an independent category with a recurrence risk higher than that of AF detected after stroke (AFDAS). However, it is unknown whether this risk difference is confounded by pre-existing anticoagulation, which is most common in KAF and also indicates a high ischemic stroke recurrence risk.

Methods

Individual patient data analysis from 5 prospective cohorts of anticoagulated patients following AF-associated ischemic stroke. We compared the primary (ischemic stroke recurrence) and secondary outcome (all-cause death) among patients with AFDAS versus KAF and among anticoagulation-naïve versus previously anticoagulated patients using multivariable Cox, Fine-Gray models, and goodness-of-fi

SUBMITTER: Lyrer F 

PROVIDER: S-EPMC10953352 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature