High rate of high-risk human papillomavirus among benign and breast cancer patients in Ethiopia.

ABSTRACT:

Introduction

There have been numerous studies that showed the presence of human papillomavirus (HPV) in breast cancer; nonetheless, there is ongoing debate regarding their association. Given few studies in Ethiopia, we aimed to investigate the magnitude of HPV infection in Ethiopian breast cancer patients.

Methods

A total of 120 formalin-fixed paraffin-embedded (FFPE) tissue blocks were obtained, and basic demographic, clinical, and histological data were collected from medical records. DNA was extracted from archived FFPE breast tissue specimens using GeneRead DNA FFPE Kit. The AnyplexTM II HPV28 Detection Kit (Seegene, Korea) was used to detect HPV by following the manufacturer's instructions. The SPSS Version 25 was used to enter and analyze data.

Results

Among the

SUBMITTER: Belachew EB 

PROVIDER: S-EPMC10954173 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature