The association between zinc and prostate cancer development: A systematic review and meta-analysis.

ABSTRACT:

Background

Prostate cancer is affecting males globally, with several complications. Zinc can play roles in cancers. We aimed to clarify the association between zinc levels or intake with prostate cancer development.

Methods

We searched PubMed, EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL), and Web of Science until May 1, 2023. We included case-controls and cross-sectionals that measured zinc level and/or intake in patients with prostate cancer or cohorts that evaluated the association between zinc and prostate cancer development. Studies that did not have a healthy control group were excluded. Joanna Briggs Institute was used for quality assessment. Publication bias was evaluated using Egger's and Begg's tests and funnel plot.

Results

Overall, 52 st

SUBMITTER: Shahrokhi Nejad S 

PROVIDER: S-EPMC10954196 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature