The role of comorbidities, medications, and social determinants of health in understanding urban-rural outcome differences among patients with heart failure.

ABSTRACT:

Purpose

There is now a 20% disparity in all-cause, excess deaths between urban and rural areas, much of which is driven by disparities in cardiovascular death. We sought to explain the sources of these disparities for Medicare beneficiaries with heart failure with reduced ejection fraction (HFrEF).

Methods

Using a sample of Medicare Parts A, B, and D, we created a cohort of 389,528 fee-for-service beneficiaries with at least 1 heart failure hospitalization from 2008 to 2017. The primary outcome was 30-day mortality after discharge; 1-year mortality, readmissions, and return emergency room (ER) admissions were secondary outcomes. We used hierarchical, logistic regression modeling to determine the contribution of comorbidities, guideline-directed medical therapy (GDMT), and so

SUBMITTER: Zeitler EP 

PROVIDER: S-EPMC10954420 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature