RNAvigate: efficient exploration of RNA chemical probing datasets.

ABSTRACT: Chemical probing technologies enable high-throughput examination of diverse structural features of RNA, including local nucleotide flexibility, RNA secondary structure, protein and ligand binding, through-space interaction networks, and multistate structural ensembles. Deep understanding of RNA structure-function relationships typically requires evaluating a system under structure- and function-altering conditions, linking these data with additional information, and visualizing multilayered relationships. Current platforms lack the broad accessibility, flexibility and efficiency needed to iterate on integrative analyses of these diverse, complex data. Here, we share the RNA visualization and graphical analysis toolset RNAvigate, a straightforward and flexible Python library that automatica

SUBMITTER: Irving PS 

PROVIDER: S-EPMC10954457 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature