Primary glioblastoma multiform (GBM) of the optic nerve and chiasma: A case report and systematic review of the literature.

ABSTRACT:

Key clinical message

Primary GBM of the optic nerve and chiasma should be included in the differential diagnosis of progressive lesions despite initial treatment; clinicians should avoid delay in confirming the histology to initiate proper treatment and improve prognosis.

Abstract

Primary GBM of the optic nerve or chiasma is very rare. The characteristics of this condition have not been well-described, which poses difficulties in establishing the correct diagnosis, affecting the treatment and the prognosis. We present a case of GBM of the optic chiasma diagnosed through an open biopsy at our centre. Following the PRISMA statement, we also conducted a systematic review after protocol registration in PROSPERO (CRD42021285855). We searched Medline and Embase through Ovid from i

SUBMITTER: Mulhem A 

PROVIDER: S-EPMC10954565 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature