Inhibitory effect of benzocaine from Schisandra chinensis on Alternaria alternata.

ABSTRACT: The clinical effects of Schisandra chinensis against human disease are well-documented; however, studies on its application in controlling plant pathogens are limited. Here, we investigated its inhibitory effect on the growth of Alternaria alternata, a fungus which causes significant post-harvest losses on apples, known as black spot disease. S. chinensis fruit extract exhibited strong inhibitory effects on the growth of A. alternata with an EC₅₀ of 1882.00 mg/L. There were 157 compounds identified in the extract by high performance liquid chromatography-mass spectrometry, where benzocaine constituted 14.19% of the extract. Antifungal experiments showed that the inhibitory activity of benzocaine on A. alternata was 43.77-fold higher than the crude extract. The application of ben

SUBMITTER: Long LF 

PROVIDER: S-EPMC10954763 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature