Clinical presentation, management, and outcome of suspected central nervous system infections in Indonesia: a prospective cohort study.

ABSTRACT:

Background

Little is known about the etiology, clinical presentation, management, and outcome of central nervous system (CNS) infections in Indonesia, a country with a high burden of infectious diseases and a rising prevalence of HIV.

Methods

We included adult patients with suspected CNS infections at two referral hospitals in a prospective cohort between April 2019 and December 2021. Clinical, laboratory, and radiological assessments were standardized. We recorded initial and final diagnoses, treatments, and outcomes during 6 months of follow-up.

Results

Of 1051 patients screened, 793 were diagnosed with a CNS infection. Patients (median age 33 years, 62% male, 38% HIV-infected) presented a median of 14 days (IQR 7-30) after symptom onset, often with altered consciou

SUBMITTER: Maharani K 

PROVIDER: S-EPMC10954958 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature