Dataset Information

Hybrid Balloon Mitral Valvuloplasty in an Adult Dog with Congenital Mitral Stenosis and Left Atrial Thrombus.

ABSTRACT:

SUBMITTER: Winter RL

PROVIDER: S-EPMC10955085 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Hybrid Balloon Mitral Valvuloplasty in an Adult Dog with Congenital Mitral Stenosis and Left Atrial Thrombus.

Winter Randolph L RL Hlusko Katelyn C KC Tillson D Michael DM Maneval Kara L KL Ferrel Claudia Serrano CS Rajeev Meenakshi M Castro Douglas D

CASE (Philadelphia, Pa.) 20240308 3Part A

PMID: 38524966

Similar Datasets

Project description:AimsThe aim of the study was to evaluate left ventricular (LV) remodeling and systolic function using two-dimensional speckle tracking echocardiographic (2D STE) imaging in children at a long-term (more than 36 months, 107.5±57.8 months) after balloon valvuloplasty for aortic stenosis (BAV).Methods and results40 patients (mean age 9,68 years, 75% male) after BAV and 62 control subjects matched to the age and heart rate were prospectively evaluated. The 2D STE assessment of LV longitudinal and circumferential strain and strain rate was performed. Left ventricular eccentric hypertrophy (LVEH) was diagnosed in 75% of patients in the study group. Left ventricular ejection fraction (LVEF) was normal in all patients. In study group, global longitudinal strain (GLS), global longitudinal strain rate (GLSr) were significantly lower compared with the controls: GLS (-19.7±2.22% vs. -22.3±1.5%, P< 0.001), GLSr (-0.89±0.15/s vs. -1.04 ±0.12/s, P < 0.001). Regional (basal, middle and apical segments) strain and strain rate were also lower compared with control group. Global circumferential strain (GCS), global circumferential strain rate (GCSr) as well as regional (basal, middle and apical segments) strain and strain rate were normal. Multivariable logistic regression analysis included: instantaneous peak systolic Doppler gradient across aortic valve (PGmax), grade of aortic regurgitation (AR), left ventricular mass index (LVMI), left ventricular relative wall thickness (LVRWT), left ventricular end-diastolic diameter (LVEDd), peak systolic mitral annular velocity of the septal and lateral corner (S'spt, S'lat), LVEF before BAV and time after BAV and showed that the only predictor of reduced GLS was LV eccentric hypertrophy [odds ratio 6.9; (95% CI: 1.37-12.5), P = 0.045].ConclusionPatients at long-term observation after BAV present the subclinical LV systolic impairment, which is associated with the presence of its remodeling. Longitudinal deformation is the most sensitive marker of LV systolic impairment in this group of patients.

Dataset Information

Hybrid Balloon Mitral Valvuloplasty in an Adult Dog with Congenital Mitral Stenosis and Left Atrial Thrombus.

Publications

Hybrid Balloon Mitral Valvuloplasty in an Adult Dog with Congenital Mitral Stenosis and Left Atrial Thrombus.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets