Overcoming barriers for left atrial appendage thrombus: a systematic review of left atrial appendage closure.

ABSTRACT:

Background

Approximately 90% of intracardial thrombi originate from the left atrial appendage in non-valvular atrial fibrillation patients. Even with anticoagulant therapy, left atrial appendage thrombus (LAAT) still occurs in 8% of patients. While left atrial appendage closure (LAAC) could be a promising alternative, the current consensus considers LAAT a contraindication to LAAC. However, the feasibility and safety of LAAC in patients with LAAT have yet to be determined.

Methods

This systematic review synthesizes published data to explore the feasibility and safety of LAAC for patients with LAAT.

Results

This study included a total of 136 patients with LAATs who underwent successful LAAC. The Amulet Amplatzer device was the most frequently utilized device (48.5%). A

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC10956221 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature