Impact of residual microcalcifcations on prognosis after neoadjuvant chemotherapy in breast cancer patients.

ABSTRACT:

Background

Residual microcalcifications after neoadjuvant chemotherapy (NAC) are challenging for deciding extent of surgery and questionable for impact on prognosis. We investigated changes in the extent and patterns of microcalcifications before and after NAC and correlated them with pathologic response. We also compared prognosis of patients depending on presence of residual microcalcifications after NAC.

Methods

A total of 323 patients with invasive breast carcinoma treated with neoadjuvant chemotherapy at Kangbuk Samsung Hospital and Samsung Medical center from March 2015 to September 2018 were included. Patients were divided into four groups according to pathologic response and residual microcalcifications. Non-pCR_w/mic group was defined as breast non-pCR wit

SUBMITTER: Kim EY 

PROVIDER: S-EPMC10956337 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature