Evaluation of plasma vitamin E and development of proteinuria in hypertensive patients.

ABSTRACT:

Background

The prospective relationship between plasma vitamin E levels and proteinuria remains uncertain. We aimed to evaluate the association between baseline plasma vitamin E levels and the development of proteinuria and examine any possible effect modifiers in patients with hypertension.

Methods

This was a post hoc analysis of the renal sub-study of the China Stroke Primary Prevention Trial (CSPPT). In total, 780 participants with vitamin E measurements and without proteinuria at baseline were included in the current study. The study outcome was the development of proteinuria, defined as a urine dipstick reading of a trace or ≥ 1+ at the exit visit.

Results

During a median follow-up duration of 4.4 years, the development of proteinuria occurred in 93 (11.9%) parti

SUBMITTER: He P 

PROVIDER: S-EPMC10956724 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature