Molecular and phylogenetic characterization of the monkeypox outbreak in the South of Spain.

ABSTRACT:

Background and aim

Until the May 2022 Monkeypox (MPXV) outbreak, which spread rapidly to many non-endemic countries, the virus was considered a viral zoonosis limited to some African countries. The Andalusian circuit of genomic surveillance was rapidly applied to characterize the MPXV outbreak in the South of Spain.

Methods

Whole genome sequencing was used to obtain the genomic profiles of samples collected across the south of Spain, representative of all the provinces of Andalusia. Phylogenetic analysis was used to study the relationship of the isolates and the available sequences of the 2022 outbreak.

Results

Whole genome sequencing of a total of 160 MPXV viruses from the different provinces that reported cases were obtained. Interestingly, we report the sequences o

SUBMITTER: Casimiro-Soriguer CS 

PROVIDER: S-EPMC10957719 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature