Phthalate metabolites and sex steroid hormones in relation to obesity in US adults: NHANES 2013-2016.

ABSTRACT:

Background

Obesity and metabolic syndrome pose significant health challenges in the United States (US), with connections to disruptions in sex hormone regulation. The increasing prevalence of obesity and metabolic syndrome might be associated with exposure to phthalates (PAEs). Further exploration of the impact of PAEs on obesity is crucial, particularly from a sex hormone perspective.

Methods

A total of 7780 adult participants in the National Health and Nutrition Examination Survey (NHANES) from 2013 to 2016 were included in the study. Principal component analysis (PCA) coupled with multinomial logistic regression was employed to elucidate the association between urinary PAEs metabolite concentrations and the likelihood of obesity. Weighted quartiles sum (WQS) regression wa

SUBMITTER: Zhang J 

PROVIDER: S-EPMC10957739 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature