Indications affect neonatal outcomes following early rescue ICSI: a retrospective study.

ABSTRACT:

Purpose

To investigate the impact of heterogeneity in patient indications or insemination protocols on neonatal outcomes of singletons following early rescue ICSI (rICSI) treatments.

Methods

A retrospective study was conducted. Propensity score matching and multivariable logistic regression were used to adjust for confounders and biases.

Results

A total of 9095 IVF patients, 2063 ICSI patients, and 642 early rICSI patients were included in the study. No differences were detected in neonatal outcomes except small for gestational age (SGA) which increased in early rICSI patients compared with both unmatched and matched IVF groups with the risk ratio (RR) of 1.31 (95% CI: 1.05, 1.64) and 1.49 (95% CI: 1.05, 2.12). Further analysis showed that SGA increased significantly

SUBMITTER: Geng J 

PROVIDER: S-EPMC10957842 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature