Quality reporting of randomized controlled trials on SGLT2 inhibitors for heart failure: a comprehensive assessment.

ABSTRACT: Randomised controlled trials (RCTs) provide clinicians with the best evidence of the effectiveness of an intervention, and complete and transparent trial reports help to critically assess and use trial results. The objective of our study was to assess the quality of reporting in RCTs of sodium-glucose co-transporter protein 2 (SGLT2) inhibitors for heart failure (HF) and identify factors associated with improved reporting quality. Two researchers conducted a comprehensive search in four databases (PubMed, Web of Science, EMBASE, and Cochrane). The quality of each report was assessed using a 25-point Overall Quality Score (OQS) based on the guidelines provided in the 2010 Consolidated Standards for Reporting of Trials (CONSORT) statement. We included a total of 58 relevant RCTs. The median

SUBMITTER: Yang Y 

PROVIDER: S-EPMC10958037 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature