Vigorous vs. moderate exercise to improve glucose metabolism in inactive women with polycystic ovary syndrome and insulin resistance: a pilot randomized controlled trial of two home-based exercise routines.

ABSTRACT:

Objective

To study the impact of vigorous vs. moderate exercise on metabolic parameters in polycystic ovary syndrome (PCOS).

Design

Randomized controlled trial.

Setting

Unsupervised home-based exercise program.

Patients

Patients with PCOS on the basis of the Rotterdam criteria with insulin resistance.

Interventions

Participants were block randomized to a home-based exercise program of 75 minutes of vigorous exercise or 150 minutes of moderate exercise per week, for 8 weeks total.

Main outcome measures

Changes in glucose, insulin, and insulin resistance.

Results

In total, 36 participants were randomized, of whom 20 completed the study. The percentage changes from baseline at 4 and 8 weeks for fasting glucose, insulin, and homeostatic model a

SUBMITTER: Wang A 

PROVIDER: S-EPMC10958708 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature