Incremental value of left ventricular shape parameters measured by gated SPECT MPI in predicting the super-response to CRT.

ABSTRACT:

Background

The purpose of this study was to evaluate the predictive value of left ventricular (LV) shape parameters measured by gated SPECT myocardial perfusion imaging (MPI) in super-responders enrolled in the VISION-CRT trial.

Methods

One hundred and ninety-nine patients who met standard criteria for CRT from multiple centers were enrolled in this study. End-systolic eccentricity (ESE) and end-diastolic eccentricity (EDE) were measures of LV shape. Super-responders were the patients who had a relative increase in left ventricular ejection fraction (LVEF) ≥ 15%.

Results

Complete data were obtained in 165 patients, and 43.6% of them were classified as super-responders. ESE was an independent predictor of CRT super-responders in univariate (OR 12.59, 95% CI 1.56-101.35

SUBMITTER: He Z 

PROVIDER: S-EPMC10959067 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature