Dataset Information

COVID-19 vaccine uptake among young adults: Influence of asthma and sociodemographic factors.

ABSTRACT:

Background

Asthma was initially described as a risk factor for severe coronavirus disease 2019 (COVID-19), but the uptake of COVID-19 vaccine among young adults with asthma is not well studied.

Objective

The aims were to assess COVID-19 vaccine uptake among young adults in general and to explore potential determinants including sociodemographic factors and asthma.

Methods

Participants from the population-based birth cohort BAMSE (Barn/Child, Allergy, Milieu, Stockholm, Epidemiology) were included: 4,064 in the study population, 3,064 in a follow-up at age 24 years, and 2,049 in a COVID-19 follow-up (mean age, 26.5 years). Asthma and asthma-associated characteristics were assessed through questionnaires and clinical data. Data on all COVID-19 vaccines registered between January 1, 2021, and February 15, 2023, were extracted from the National Vaccination Register.

Results

In the study population (n = 4,064), 53.9% had ≥3 COVID-19 vaccine doses registered. In the 24-year follow-up population (n = 3,064), vaccine uptake differed in relation to education (P < .001). Among the participants with university/college education, 65.7% had an uptake of ≥3 doses of vaccine, compared to 54.1% among the participants with elementary school/high school education. Participants with asthma had decreased odds of receiving ≥3 doses (adjusted odds ratio = 0.62; 95% confidence interval, 0.41-0.92) and ≥2 compared to peers without asthma. Those with uncontrolled disease also had decreased odds of receiving ≥3 doses (adjusted odds ratio = 0.30; 95% confidence interval, 0.13-0.66) and ≥2 compared to participants with controlled asthma.

Conclusions

COVID-19 vaccine uptake among young adults is lower in individuals from households with lower socioeconomic status and among those with asthma, including uncontrolled asthma.

SUBMITTER: Odling M

PROVIDER: S-EPMC10959661 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature

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Publications

COVID-19 vaccine uptake among young adults: Influence of asthma and sociodemographic factors.

Ödling Maria M Andersson Niklas N Ekström Sandra S Roxhed Niclas N Schwenk Jochen M JM Björkander Sophia S Bergström Anna A Melén Erik E Kull Inger I

The journal of allergy and clinical immunology. Global 20240220 2

<h4>Background</h4>Asthma was initially described as a risk factor for severe coronavirus disease 2019 (COVID-19), but the uptake of COVID-19 vaccine among young adults with asthma is not well studied.<h4>Objective</h4>The aims were to assess COVID-19 vaccine uptake among young adults in general and to explore potential determinants including sociodemographic factors and asthma.<h4>Methods</h4>Participants from the population-based birth cohort BAMSE (Barn/Child, Allergy, Milieu, Stockholm, Epid ...[more]

PMID: 38524785

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Project description:BackgroundIn Central America, Honduras experienced a significant increase in SARS-CoV-2 infections between March 11, 2020, and January 26, 2022. Although limited research has been conducted on the impact of the COVID-19 pandemic on populations in Central American countries, this study seeks to contribute to the existing body of knowledge in the region. The objective of this study was to investigate the variability of COVID-19 mortality in Honduras and the impact of sociodemographic factors.MethodsA cross-sectional and ecological study, using data from cases collected by the National Risk Management System (SINAGER) and recorded by the Demographic Observatory of the National Autonomous University of Honduras (ODU) between March 11, 2020, and January 26, 2022. Sociodemographic variables were obtained from the 2013 XVII Population and VI Housing Census by the National Institute of Statistics (INE). Age-adjusted case and COVID-19 mortality rates by sex were calculated. To explain the potential causes of variability, multilevel logistic regression models were constructed, considering individual and contextual variables.ResultsA total of 513,416 COVID-19 cases were included, of which 98 % (503,176) survived and 2 % (10,240) died. The results showed differences in COVID-19 mortality rates between municipalities and departments. The multilevel model revealed that age (OR: 1.0737; 95 % CI: [1.0726; 1.0749]) and sex (OR: 0.7434; 95 % CI: [0.7027; 0.7841]) were significantly associated with COVID-19 mortality, with men being more likely to die. Among departments, the significant contextual factors were the illiteracy rate and the percentage of the rural population, both of which were associated with higher COVID-19 mortality (OR: 1.0850; 95 % CI: [1.0511; 1.1189] and OR: 1.0234; 95 % CI: [1.0146; 1.0323]), while the percentage of the active population (working age people) was associated with a decrease in COVID-19 mortality (OR: 0.9768; 95 % CI: [0.9591; 0.9944]). The intraclass correlation coefficient (ICC) showed a reduction in variability attributable to the variation between departments, with a final ICC of 0.68 % .ConclusionsDifferences in COVID-19 mortality were found between the different departments, partly explained by sociodemographic factors. The results of this study show that, in addition to individual characteristics, population-level socioeconomic and educational factors influence COVID-19 mortality. Multilevel analysis is highly useful for providing evidence to improve approaches in future pandemics.

Dataset Information

COVID-19 vaccine uptake among young adults: Influence of asthma and sociodemographic factors.

Background

Objective

Methods

Results

Conclusions

Publications

COVID-19 vaccine uptake among young adults: Influence of asthma and sociodemographic factors.

Similar Datasets

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