Intraoperative Evaluation of Breast Tissues During Breast Cancer Operations Using the MasSpec Pen.

ABSTRACT:

Importance

Surgery with complete tumor resection remains the main treatment option for patients with breast cancer. Yet, current technologies are limited in providing accurate assessment of breast tissue in vivo, warranting development of new technologies for surgical guidance.

Objective

To evaluate the performance of the MasSpec Pen for accurate intraoperative assessment of breast tissues and surgical margins based on metabolic and lipid information.

Design, setting, and participants

In this diagnostic study conducted between February 23, 2017, and August 19, 2021, the mass spectrometry-based device was used to analyze healthy breast and invasive ductal carcinoma (IDC) banked tissue samples from adult patients undergoing breast surgery for ductal carcinomas or nonmal

SUBMITTER: Garza KY 

PROVIDER: S-EPMC10960202 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature