Regional variation of COVID-19 admissions, acute kidney injury and mortality in England - a national observational study using administrative data.

ABSTRACT:

Background

This study explores regional variations in COVID-19 hospitalization rates, in-hospital mortality, and acute kidney injury (AKI) in England. We investigated the influence of population demographic characteristics, viral strain changes, and therapeutic advances on clinical outcomes.

Methods

Using hospital episode statistics, we conducted a retrospective cohort study with 749,844 admissions in 337,029 adult patients with laboratory-confirmed COVID-19 infection (March 1, 2020, to March 31, 2021). Multivariable logistic regression identified factors predicting AKI and mortality in COVID-19 hospitalized patients.

Results

London had the highest number of COVID-19 admissions (131,338, 18%), followed by the North-west region (122,683, 16%). The North-west had the hi

SUBMITTER: Kolhe NV 

PROVIDER: S-EPMC10960376 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature