One-year regional brain volume changes as potential predictors of cognitive function in multiple sclerosis: a pilot study.

ABSTRACT:

Background

The most reliable magnetic resonance imaging (MRI) marker of cognitive dysfunction in multiple sclerosis (MS) is brain atrophy. However, 1-year volumetric changes prior to cognitive assessment were never studied as potential predictors of cognition, which we aim to assess with this pilot work.

Methods

Twenty-two MS patients were submitted to a baseline measure of 83 regional brain volumes with MRI and re-evaluated 1 year later; they were also tested with the Brief International Cognitive Assessment for MS (BICAMS): sustained attention and processing speed were examined with the Symbol Digit Modalities Test (SDMT), verbal and visuo-spatial learning and memory with the learning trials from the California Verbal Learning Test-II (CVLT) and the Brief Visuo-spatial Mem

SUBMITTER: Meira T 

PROVIDER: S-EPMC10961282 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature